Objective: to develop and validate an educational technology for individuals living with the human immunodeficiency virus.Method: a methodological study, for the elaboration of educational material.The educational needs, content selection, and illustrations were defined from interviews with the target population.Afterward, we carried the writing, t
Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas
Abstract The microbiome is fundamentally one of the most unique organs in the human body.Dysbiosis can result in critical inflammatory responses and result in pathogenesis contributing to neoplastic events.We used a pan-pathogen array technology (PathoChip) coupled with next-generation sequencing to establish microbial signatures unique to human or
Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis
Abstract Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures.In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown.Here we show that autophagy, a major catabolic process required for the maintenance of bone homeostasis and bone growth, is
Status of Sanitation in the Rural Areas of a Health Unit Dis-trict, Tamil Nadu, India
Background: Sanitation is the key to better health.Even towards the end of the millennium development goal era, provision of sanitation still continues to be a challenge especially in rural areas.Objectives: The present study was undertaken to describe the availability and utility of sanitary latrines in study population and to assess knowledge / p